THERAPEUTIC EFFECT OF GINGER, ALOE, BEE HONEY AND THEIR MIXTURE ON CHRONIC LIVER DAMAGE AND FlBROSlS INDUCED BY CCI4 IN RATS

Document Type : Original Article

Authors

1 Department of Biochemistry, Faculty of Agriculture, Cairo University.

2 Department of special Food, Agriculture Research Center.

3 Department of Pathology, Fac‘ulty of Veterinary Medicine, Cairo University.

Abstract

The purpose of this study was to evaluate the hepatoprotective and
antifibrotic potential of ginger, aloe, bee honey and their mixture on chronic liver injury
induced by CCIi for 8 weeks. The results exhibited that the increase of serum alanine
aminofransferase (SALT). serum aspartate aminotransferase (sAST). alkaline
phosphatase (sALP) activities. total and direct biiirubin as well as liver homogenate
thiobarbituric acid reactive substances (TEARS) in CCIa liver injury were significantly
reduced by treatment with ginger (9.1glkg ow), aloe (0.5glkg b. w). bee honey {as
glkg b. w.) and their mixture, five times in a week. The aforementioned materials
reduced the collagen content by 69%, 667%. 62.85% and 68.65%, respectively. The
results were comparable to silymarin (25mg! kg bw.)

Keywords

Journal of Soil Sciences and Agricultural Engineering
Volume 31, Issue 2
February 2006
Pages 1151-1163

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