BIOLOGICAL EFFECT OF HIGH DIETARY FATS AND SUCROSE LEVEL ON LIVER FUNCTIONS AND LIPIDS PROFILE IN THE EXPERIMENTAL RATS

The effect of a diet containing 25% edible fats (balady butler,balady samna.
and hydrogenated fat); edible oils (corn oil, sunflower oil and mixed oil) and a diet
containing 45% sucrose on body weight gain; organs weight (liver, kidney and
splelen); liver enzymes (AL T and AST); lipid profile (Triglycerides, Total cholesterol
(T.ch.), High density lipoprotein cholesterol (HDL-Ch), Low density Iipoprotein(LDL-Ch)
and Total protein (TP). T he risk ratio is the result 0 f T .ch divided by H DL-ch were
studied in the experimental rats. The feeding experimental was carried out during 45
days and the results were compared with control group of rats fed a balanced diet.
The results showed that groups of rats fed on diet containing (25% edible fat and/or
45% sucrose) caused significant increase in body weight gain, organs weight, level of
liver enzymes and lipid profiles of serum and liver extract, while slightly decreased in
total protein was observed when compared with control. On the other side, data
showed that no changes were observed for groups of rats fed on 25% edible oils on
body weight gain, organs weight, liver enzymes, lipids profile and total protein
comparing with control. While, the tow-tat (5%) group in rats diet yielded a significant
decrease in the all previously parameters than control. this is due to the low fat
content in the feeding diets of rats. In conclusion, although 25% edible oils was high
fat diet. but it was less harmful effect on the liver functions and lipids profile than that
recorded for the 25% edible fats (Saturated fatly acids) and thus it can be represented
the 25% edible oils (unsaturated fatty acids) was healthy diet for the experimental
rats.