CHEMICAL STUDY OF VOLATILE OIL OF FRESH AND DRY LEAVES SAGE (Sa/via fruficosa) AND ITS ANTIBACTERIAL ACTIVITY

Document Type : Original Article

Authors

1 Department of Food Science and Technology, College of Agriculture, University of Omar EL- Mukhtar, Libya

2 Faculty of Pharmacy, University of Omar EL- Mukhtar, Libya

3 Dept. of Zoology, College of Sci., Univ. of Omar EL- Mukhtar, Libya

4 Dept. of Botany, College of Sci., Univ. of Omar EL- Mukhtar, Libya

Abstract

The volatile oil of Salvia fruticosa which was extracted from the dry and
fresh green leaves using hydrodistillation had a yellow color/aromatic and its
percentage was (0.7,0.3)% respectively. The oil was studded for its
constitutes by GC-MS . The results showed the high presence of ten
components (1,e-Cineole, 1,e-Cineol Isomer ,Camphor, 'rrans-p
Caryophyllene .o-Plnene . ~-Myrcene, Linalool . a.- Terpineol, «-Terptneol
isomer, a.-Camphene ) in dry leaves and three components (1,8-Cineol
Isomer .campnor .c-Terpineol isomer) in fresh leaves.
Antibacterial study showed that the volatile oil extract from dry leaves
inhibited the growth of E. coli I K. pneumonia, S. aureus and P. mirabilis
with an inhibition zone approximately (5.6, 5.3, 5.7, 4.6) mm respectively.
However the oil extract from fresh leaves showed a significant inhibitory
effect toward S. aureus , with an inhibition zone about 22 mm. this result was
very close to the neomycin as positive control (20 mm). On the other hand
there was not any activity against the other three species of the bacteria used
in this study.